Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Surface Membrane Barriers01:18

Surface Membrane Barriers

3.3K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
3.3K
Epithelial Tissues and Their Functions01:23

Epithelial Tissues and Their Functions

42.9K
Epithelial tissues are large sheets of cells covering all of the surfaces of the body. These surfaces can be internal or external, for example, skin, airways, the digestive tract, the urinary system, and the reproductive system. Hollow organs and body cavities that do not connect to the body's exterior, including blood vessels and serous membranes, are lined by epithelial tissue known as the endothelium.
Epithelial tissues provide the body's first line of protection from physical,...
42.9K
Tight Junctions01:29

Tight Junctions

8.4K
Tight junctions are molecular seals between cells that prevent the leaking of fluids, ions, and other small solutes across cavities and compartments in multicellular organisms. They are mainly composed of claudin and occludin transmembrane proteins, and other proteins such as tricellulin and JAM (junctional adhesion molecule). All these proteins are 4-pass transmembrane proteins, except JAM, which is a single-pass transmembrane protein belonging to the immunoglobulin superfamily. The...
8.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Jejunal undifferentiated carcinoma with multiple metastases involving the right palatine tonsil: a case report].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2026
Same author

[Epidemiological characteristics of typhoid fever and paratyphoid fever outbreaks in China from 2008 to 2024].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2026
Same author

[Efficiency and safety of JAK inhibitors for alopecia totalis and alopecia universalis].

Zhonghua yi xue za zhi·2025
Same author

[Genomic profiles of primary and acquired MET mutations in NSCLC and the impact of co-mutations on treatment outcomes].

Zhonghua yi xue za zhi·2025
Same author

[The influence of two-way referral model on treatment and prognosis of patients with chronic heart failure].

Zhonghua xin xue guan bing za zhi·2025
Same author

[Epidemiological characteristics of bacillary dysentery in China, 2005-2024].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2025
Same journal

[The era of precision diagnosis and treatment for optic neuritis: advances in diagnostic classification, biomarkers and therapeutic strategies].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same journal

[Application value of ocular multimodal imaging methods in the evaluation of increased intracranial pressure].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same journal

[Secondary panuveitis after ocular wasp sting: a case report].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same journal

[Correlation of ocular surface changes with filtering bleb morphology after antiglaucoma surgery for primary angle-closure glaucoma].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same journal

[Regulation of SARM1 on SNPH expression and its participation in glaucomatous optic neuropathy].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
Same journal

[Construction of a regulated <i>Crat</i> overexpression system in mouse hippocampal neuronal HT22 cell line].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology·2026
See all related articles

Related Experiment Video

Updated: Mar 15, 2026

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
07:28

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing

Published on: July 10, 2018

21.5K

[Recent studies on corneal epithelial barrier function].

F F Liu1, W Li, Z G Liu

  • 1Ophthalmological Research Institute, Xiamen University, Fujian Ophthalmology & Visual Sciences Key Lab., Xiamen 361000, China.

[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|August 27, 2016
PubMed
Summary
This summary is machine-generated.

The corneal epithelial barrier protects the eye from foreign materials. Its dysfunction is linked to various eye diseases, highlighting its critical role in ocular health.

More Related Videos

Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium
07:10

Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium

Published on: April 6, 2022

4.8K
An Epithelial Abrasion Model for Studying Corneal Wound Healing
04:45

An Epithelial Abrasion Model for Studying Corneal Wound Healing

Published on: December 29, 2021

4.0K

Related Experiment Videos

Last Updated: Mar 15, 2026

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
07:28

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing

Published on: July 10, 2018

21.5K
Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium
07:10

Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium

Published on: April 6, 2022

4.8K
An Epithelial Abrasion Model for Studying Corneal Wound Healing
04:45

An Epithelial Abrasion Model for Studying Corneal Wound Healing

Published on: December 29, 2021

4.0K

Area of Science:

  • Ophthalmology
  • Cell Biology
  • Physiology

Background:

  • The corneal epithelium is the eye's outermost protective layer.
  • It forms a selective permeability barrier crucial for nutrient uptake and preventing pathogen invasion.
  • Disruptions in this barrier are implicated in numerous ocular diseases.

Purpose of the Study:

  • To review recent research on the corneal epithelial barrier.
  • To highlight its structure, function, and influencing factors.

Main Methods:

  • Literature review of clinical and experimental studies.
  • Synthesis of findings on corneal epithelial barrier properties.

Main Results:

  • Abnormal corneal epithelial barrier function is a pathological basis for many ocular diseases.
  • The barrier involves proteins regulating cell proliferation, differentiation, and apoptosis.
  • Factors influencing barrier integrity were examined.

Conclusions:

  • The corneal epithelial barrier is vital for maintaining ocular health.
  • Understanding its structure, function, and influencing factors is crucial for treating eye diseases.