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In vitro evaluation of remineralization efficacy of different calcium- and fluoride-based delivery systems on
Aparajita Gangrade1, Vandana Gade1, Sanjay Patil1
1Department of Conservative Dentistry and Endodontics, Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Nagpur, Maharashtra, India.
Background:
Caries is the most common dental disease facing the world population. Caries can be prevented by remineralizing early enamel lesions.
Aim:
To evaluate remineralization efficacy of stannous fluoride (SnF2), casein phosphopeptide-amorphous calcium phosphate with fluoride (CPP-ACPF) and calcium sucrose phosphate (CaSP).
Materials And Methods:
Fifty enamel samples were taken; they were divided into five groups (n = 10). Demineralization was carried out with Groups A, B, C, and E. Remineralization was carried out with Groups A, B, and C for 7 days using SnF2, CPP-ACPF, and CaSP, respectively. In Group D, no surface treatment was carried out, to mark as positive control whereas Group E was kept as negative control with only surface demineralization of enamel. Enamel microhardness was tested using Vickers's microhardness tester after 7 day remineralization regime.
Statistical Analysis:
One-way analysis of variance and post hoc Tukey tests were performed.
Results:
The mean microhardness values in descending order: Positive control > SnF2> CaSP > CPP-ACPF > negative control.
Conclusion:
All remineralizing agents showed improved surface remineralization. However, complete remineralization did not occur within 7 days. SnF2 showed the highest potential for remineralization followed by CaSP and CPP-ACPF.
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