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Published on: February 9, 2011
Microbiologic contamination of a positive- and a neutral- displacement needleless intravenous access device in
A L Casey1, T J Karpanen1, P Nightingale2
1Department of Clinical Microbiology, University Hospitals Birmingham National Health Service Foundation Trust, The Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham, UK; Research and Development, University Hospitals Birmingham National Health Service Foundation Trust, The Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham, UK.
Abstract:
The use of a positive-displacement needleless intravenous access device was associated with lower microbial contamination rates compared with a neutral-displacement device when used on central venous catheters in hemato-oncology patients. In addition, rates of central line-associated bloodstream infection did not differ when either device was used.
Insights
Positive-displacement needleless intravenous devices reduced microbial contamination on central venous catheters in hemato-oncology patients. However, central line-associated bloodstream infection rates remained similar between positive- and neutral-displacement devices.
Area of Science:
- Infection Control
- Medical Devices
- Hematology-Oncology
Background:
- Central venous catheters are essential for hemato-oncology patients but pose infection risks.
- Needleless intravenous access devices are used to prevent needlestick injuries and contamination.
- Different displacement technologies (positive vs. neutral) exist in needleless devices.
Purpose of the Study:
- To compare microbial contamination rates between positive-displacement and neutral-displacement needleless intravenous access devices.
- To evaluate the impact of these devices on central line-associated bloodstream infection (CLABSI) rates in hemato-oncology patients.
Main Methods:
- A comparative study involving hemato-oncology patients with central venous catheters.
- Microbial cultures were performed on the accessed devices.
- CLABSI rates were monitored and compared between the two device types.
Main Results:
- Positive-displacement needleless devices demonstrated significantly lower microbial contamination rates compared to neutral-displacement devices.
- No statistically significant difference was observed in the rates of central line-associated bloodstream infections between the two types of devices.
Conclusions:
- Positive-displacement needleless intravenous access devices may offer an advantage in reducing microbial contamination of central venous catheters.
- The choice of needleless device type did not appear to influence the incidence of CLABSIs in this patient population.
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