Microbiologic contamination of a positive- and a neutral- displacement needleless intravenous access device in

A L Casey1, T J Karpanen1, P Nightingale2

  • 1Department of Clinical Microbiology, University Hospitals Birmingham National Health Service Foundation Trust, The Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham, UK; Research and Development, University Hospitals Birmingham National Health Service Foundation Trust, The Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham, UK.

Insights

Positive-displacement needleless intravenous devices reduced microbial contamination on central venous catheters in hemato-oncology patients. However, central line-associated bloodstream infection rates remained similar between positive- and neutral-displacement devices.

Area of Science:

  • Infection Control
  • Medical Devices
  • Hematology-Oncology

Background:

  • Central venous catheters are essential for hemato-oncology patients but pose infection risks.
  • Needleless intravenous access devices are used to prevent needlestick injuries and contamination.
  • Different displacement technologies (positive vs. neutral) exist in needleless devices.

Purpose of the Study:

  • To compare microbial contamination rates between positive-displacement and neutral-displacement needleless intravenous access devices.
  • To evaluate the impact of these devices on central line-associated bloodstream infection (CLABSI) rates in hemato-oncology patients.

Main Methods:

  • A comparative study involving hemato-oncology patients with central venous catheters.
  • Microbial cultures were performed on the accessed devices.
  • CLABSI rates were monitored and compared between the two device types.

Main Results:

  • Positive-displacement needleless devices demonstrated significantly lower microbial contamination rates compared to neutral-displacement devices.
  • No statistically significant difference was observed in the rates of central line-associated bloodstream infections between the two types of devices.

Conclusions:

  • Positive-displacement needleless intravenous access devices may offer an advantage in reducing microbial contamination of central venous catheters.
  • The choice of needleless device type did not appear to influence the incidence of CLABSIs in this patient population.

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