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Updated: Mar 15, 2026

Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System
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Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System

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A Single-use Strategy to Enable Manufacturing of Affordable Biologics

Renaud Jacquemart1, Melissa Vandersluis1, Mochao Zhao1

  • 1Natrix Separations Inc., 5295 John Lucas Drive, Burlington, Ontario L7L 6A8, Canada.

Computational and Structural Biotechnology Journal
|August 30, 2016
PubMed

Keywords:
Affinity membrane chromatographyAntibody manufacturing paradigmsB&E, bind and eluteCapEx, capital expenseCoG, cost of goodsContinuous bioprocessingDSP, downstream processEBA, expanded bed adsorptionEMA, European Medicines AgencyFDA, Food and Drug AdministrationFT, flow throughFlexible, single-use facilitiesHCP, host cell proteinMV, membrane volumeOpEx, operating expensePAT, process analytical technologyProcess economicsSMB, simulated moving bedUSP, upstream processcGMP, current good manufacturing practice

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