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Related Experiment Videos

The Human Connectome Project's neuroimaging approach.

Matthew F Glasser1, Stephen M Smith2, Daniel S Marcus3

  • 1Department of Neuroscience, Washington University Medical School, St. Louis, Missouri, USA.

Nature Neuroscience
|August 30, 2016
PubMed
Summary

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This study introduces an integrated neuroimaging approach, inspired by the Human Connectome Project, to advance brain research. Adopting this paradigm can accelerate discoveries in brain health and disease.

Area of Science:

  • Neuroscience
  • Medical Imaging

Background:

  • Noninvasive human neuroimaging has led to significant brain discoveries.
  • Methodological advancements in neuroimaging have been slow to be adopted.

Purpose of the Study:

  • To present an integrated data acquisition, analysis, and sharing approach for neuroimaging.
  • To promote the adoption of recent methodological advances, particularly those from the Human Connectome Project (HCP).

Main Methods:

  • The proposed 'HCP-style' paradigm includes seven core tenets.
  • These tenets cover multimodal data collection, high-resolution acquisition, artifact minimization, naturalistic data representation, cross-subject alignment, accurate parcellation analysis, and user-friendly data sharing.

Main Results:

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  • The paper illustrates the HCP-style paradigm using existing HCP datasets.
  • Guidance for future research incorporating this paradigm is provided.

    • Conclusions:

    • Widespread adoption of this integrated neuroimaging paradigm is expected to accelerate progress in understanding the brain.
    • This approach aims to enhance discoveries in both brain health and disease.