Cognitive decline: A vitamin B perspective
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Updated: Mar 15, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
Published on: February 14, 2014
Kathleen Mikkelsen1, Lily Stojanovska1, Kathy Tangalakis1
1Centre for Chronic Disease, College of Health and Biomedicine, Victoria University, P.O. Box 14426, Melbourne VIC 8001, Australia.
Abstract:
Cognitive decline is one of the major causes of disability in older people. A high level of homocysteine, a byproduct of vitamin B, has been linked to brain atrophy, which itself is a precursor to cognitive decline leading to dementia and Alzheimer's disease. In addition, a low level of vitamin B is often noted in patients with dementia and Alzheimer's disease and its supplementation has been shown to improve memory and to slow the progress of brain atrophy. This information may aid in the use of vitamin B as a preventative measure against severe cognitive decline, and thus reduce the onset of conditions such as dementia and Alzheimer's disease.
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