Related Experiment Video
Updated: Mar 15, 2026
07:14
A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
Published on: January 18, 2018
10.0K
Pain perception following different neurosurgical procedures: a quantitative prospective study.
Manju Dhandapani1, Sivashanmugam Dhandapani2, Meena Agarwal3
1a Department of Neuro-nursing , PGIMER , Chandigarh , India.
Contemporary Nurse
|August 31, 2016
Summary
Post-neurosurgery pain intensifies 13-24 hours after procedures. Infratentorial and lumbar surgeries result in significantly higher pain scores compared to other neurosurgical interventions.
Area of Science:
- Neurosurgery
- Pain Management
- Clinical Outcomes
Background:
- Post-neurosurgical pain often lacks adequate attention in clinical research.
- Understanding pain trajectories is crucial for effective patient management.
Purpose of the Study:
- To prospectively evaluate and quantify pain experienced by patients undergoing various neurosurgical procedures.
- To identify factors influencing post-neurosurgery pain levels.
Main Methods:
- A prospective study involving 159 patients undergoing cranial, spinal, or peripheral nerve surgery.
- Pain was assessed using an 11-point scale (0-10) over a 24-hour period post-operation.
- Data were analyzed concerning procedure type, location, and patient demographics.
Main Results:
- Overall mean pain scores increased significantly from 3.51 (0-12 hours) to 5.06 (13-24 hours).
- Infratentorial procedures (8.02) and lumbar surgeries (6.5) reported significantly higher pain scores compared to supratentorial (3.48) and cervical (4.04) procedures, respectively.
- Age and gender did not significantly impact pain scores.
Conclusions:
- Post-neurosurgery pain severity escalates significantly between 13-24 hours.
- Infratentorial and lumbar surgical procedures are associated with substantially greater post-operative pain.
- Targeted pain management strategies are warranted for specific neurosurgical procedures.
Related Concept Videos
01:44Nociception
33.9K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
33.9K
01:20Pain
1.7K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.7K
01:12Local Anesthetics: Adverse Effects
924
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
924
01:29Blood and Nerve Supply to the Bones
14.5K
Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
14.5K
01:24General Anesthesia: Overview
928
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
928
01:25Analgesia and Pain Management
2.7K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
2.7K