Related Experiment Video
Updated: Mar 15, 2026
A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
Published on: June 2, 2022
Detection of cardiovascular calcifications: Is it a useful tool for nephrologists?
Jordi Bover1, José Luis Górriz2, Pablo Ureña-Torres3
1Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, España.
Insights
Cardiovascular calcification in chronic kidney disease (CKD) is a key predictor of adverse outcomes. Assessing this calcification aids nephrologists in personalizing patient treatment and improving clinical decisions.
Area of Science:
- Nephrology
- Cardiology
- Biomedical Science
Background:
- Chronic kidney disease (CKD) serves as a model for understanding cardiovascular (CV) calcification.
- CV calcification is a late, secondary ossification phenomenon with significant clinical implications in CKD patients.
Purpose of the Study:
- To review the types of CV calcification in CKD patients.
- To analyze the association between CV calcification and adverse CV events and mortality.
- To justify the routine assessment of CV calcification in nephrology practice.
Main Methods:
- Comprehensive literature review.
- Analysis of existing data on CV calcification in CKD.
- Evaluation of the clinical relevance of CV calcification assessment.
Main Results:
- CV calcification is directly linked to increased CV events and mortality in CKD.
- Assessment of CV calcification is a crucial predictor of clinical outcomes.
- CV calcification assessment can guide personalized therapeutic strategies.
Conclusions:
- CV calcification is a significant factor in CKD patient outcomes.
- Nephrologists should incorporate CV calcification assessment into routine practice.
- Personalized treatment approaches are enhanced by understanding CV calcification.
Abstract:
Chronic kidney disease (CKD) has been used as a model and source of knowledge concerning the mechanisms, clinical relevance and accelerated progression of cardiovascular (CV) calcification, as well as its consequences in clinical practice, despite we know that it is a late secondary ossification phenomenon and only circumstantial evidence is available. In this comprehensive review, we firstly describe the types of CV calcification which affect CKD patients, and we analyse how its presence is directly associated with CV events and increased mortality in these patients. We also justify the use of CV calcification assessment in regular nephrology clinical practice, because CV calcification is an important predictor of clinical outcome in these patients. Consequently, we believe that CV calcification assessment is a tool that could and should be used by nephrologists when making a decision concerning individual patients, consistent with the current trend of an ever-more-personalised therapeutic approach.
More Related Videos
08:02Author Spotlight: Enhanced Quantification of Cardiovascular Calcification Progression for Longitudinal Micro PET/CT Studies in Small Research Animals
Published on: November 15, 2024
04:40Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Related Concept Videos
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
01:20Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
01:28Imaging Studies for Cardiovascular System V: CT
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
01:18Chronic Kidney Disease IV: Nursing Management
01:19Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...