Delirium as presenting symptom of neuro-Behcet's disease

Area of Science:

• Neurology
• Rheumatology
• Vascular Medicine

Background:

• Behcet's disease is a multisystemic inflammatory disorder characterized by thrombosis and vasculitis.
• Neurological manifestations, though less common, can be the initial presentation, prompting medical attention.

Observation:

• A 30-year-old female presented with acute neurological symptoms including severe headaches and confusion.
• Brain MRI revealed bilateral thalamic lesions with hemorrhage, alongside a history of recurrent oral ulcers, miscarriages, and deep venous thrombosis.

Findings:

• Differential diagnoses were excluded, leading to the establishment of Behcet's disease diagnosis.
• The case highlights neurological involvement as a presenting feature of Behcet's disease.

Implications:

• Behcet's disease should be considered in patients with unexplained neurological and systemic symptoms, particularly in endemic regions.
• Timely diagnosis and treatment are crucial, even in critical cases where alternative diagnoses are not apparent.