Related Experiment Video
Updated: Mar 15, 2026
14:51
Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype
Published on: June 17, 2022
3.7K
In Vitro-Pooled shRNA Screening to Identify Determinants of Radiosensitivity
Alessandro Ceroni1, Geoff S Higgins2, Daniel V Ebner3
1Adaptimmune Ltd, 91 Park Drive, Milton Park, Oxon, OX14 4RY, UK. alessandro_ceroni@hotmail.com.
Methods in Molecular Biology (Clifton, N.J.)
|September 2, 2016
Abstract
None:
Short hairpin RNA (shRNA)-pooled screening is a valuable and cost-effective tool for assaying the contribution of individual genes to cell viability and proliferation on a genomic scale. Here we describe the key considerations for the design and execution of a pooled shRNA screen to identify determinants of radiosensitivity.
