Related Experiment Video
Updated: Mar 15, 2026
08:53
Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
Published on: June 6, 2025
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Cognitive rehabilitation for memory deficits after stroke
Roshan das Nair1, Heather Cogger, Esme Worthington
1Division of Rehabilitation and Ageing, University of Nottingham, B98, B Floor Medical School, Queen's Medical Centre, Nottingham, UK, NG7 2UH.
The Cochrane Database of Systematic Reviews
|September 2, 2016
Summary
Cognitive rehabilitation for stroke survivors shows short-term benefits in self-reported memory but not long-term. More research is needed to confirm effectiveness for memory and other functions.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Cognitive Psychology
Background:
- Memory deficits are common after stroke, impacting daily activities.
- Cognitive rehabilitation aims to improve memory or teach coping strategies.
- Previous reviews show inconclusive evidence on rehabilitation effectiveness.
Purpose of the Study:
- To assess if cognitive rehabilitation improves memory outcomes post-stroke compared to control groups.
- To evaluate effects on subjective and objective memory, function, mood, and quality of life.
- To consider both immediate and long-term rehabilitation outcomes.
Main Methods:
- Systematic review and meta-analysis of randomized controlled trials.
- Searched multiple databases (Cochrane, MEDLINE, EMBASE, etc.) up to May 2016.
- Included 13 trials with 514 participants, assessing risk of bias and synthesizing data.
Main Results:
- Significant short-term improvement in subjective memory reports (SMD 0.36, moderate evidence).
- No significant long-term effects on subjective memory (low evidence).
- No significant effects on objective memory, functional abilities, mood, or quality of life.
Conclusions:
- Cognitive rehabilitation offers short-term subjective memory benefits post-stroke.
- Long-term benefits and effects on objective measures remain unproven.
- Limited evidence due to study quality, outcome inconsistency, and small sample sizes necessitates better-designed trials.
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