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Published on: June 13, 2021
Sleep disorders in Pregnancy: Glycaemic implications
1Departments of Endocrinology, Command Hospital, Chandimandir, India.
Insights
Sleep disorders during pregnancy negatively impact maternal and fetal health, leading to serious cardio-metabolic issues like insulin resistance and hyperglycemia. This review explores their pathophysiology and glycaemic effects.
Area of Science:
- Physiology
- Sleep Medicine
- Obstetrics
Background:
- Sleep is a vital biorhythm for bodily restoration, regulated by the circadian center.
- Sleep duration has decreased due to urbanization, increasing sleep disorders like insomnia and sleep-disordered breathing.
- Sleep disorders are linked to adverse cardio-metabolic outcomes, including insulin resistance and hyperglycemia.
Purpose of the Study:
- To review the pathophysiology of sleep disorders during pregnancy.
- To examine the glycaemic implications of sleep disorders in pregnant individuals.
- To highlight adverse foeto-maternal outcomes and long-term cardiovascular risks.
Main Methods:
- Literature review of sleep disorders during pregnancy.
- Analysis of physiological changes affecting sleep in pregnancy.
- Examination of glycaemic control and metabolic consequences.
Main Results:
- Pregnancy significantly alters physiological homeostasis, increasing susceptibility to sleep disorders.
- Sleep disorders in pregnancy are associated with adverse foeto-maternal outcomes.
- These disorders contribute to long-term cardiovascular implications and metabolic disturbances.
Conclusions:
- Sleep disorders during pregnancy present significant risks to both mother and fetus.
- Understanding the pathophysiology and glycaemic implications is crucial for managing these risks.
- Interventions addressing sleep disturbances may improve maternal and fetal health outcomes.
Abstract:
Sleep is one of the essential biorhythms of the body that helps in optimum restoration of many body functions. The sleep-wake cycle is determined by the circadian centre and is responsible for the anabolic functions in the body. Infants require about 14 to 18 hours of sleep per day, which reduces gradually to about 8 hours in adults. Urbanization and evolutionary changes have altered the sleep hygiene and shortened the sleep duration. This lead to various sleep disorders like sleep disordered breathing, insomnia and narcolepsy. Sleep disorders lead to adverse cardio-metabolic consequences, including insulin resistance and hyperglycaemia. Pregnancy poses an enormous burden on the homeostasis of the women with alteration in many physiological functions. The sleep disorders during pregnancy lead to adverse foeto-maternal outcomes with long term cardiovascular implications. In this article, I review the pathophysiology of sleep disorders during pregnancy and their glycaemic implications.
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