Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

666
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
666
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

526
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
526
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

690
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
690
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

303
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
303
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

535
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
535
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

402
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
402

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Authors' reply: comments regarding "Current evidence gaps to support systematic cytomegalovirus screening in pregnancy".

EClinicalMedicine·2026
Same author

Virulence Phenotypes Differentiate Persistent vs. Resolving Isolates of Human <i>Staphylococcus aureus</i> Bacteremia.

Antibiotics (Basel, Switzerland)·2026
Same author

Optimizing phage-antibiotic combinations: impact of administration order against daptomycin non-susceptible (DNS) MRSA clinical isolates.

Antimicrobial agents and chemotherapy·2025
Same author

Healthcare costs of invasive meningococcal disease: a nationwide population-based study using an innovative clustering method to identify sequelae.

BMC infectious diseases·2025
Same author

Diagnostic performance of 2023 endocarditis criteria in patients with and without cardiac implantable electronic devices.

Heart (British Cardiac Society)·2025
Same author

<i>Staphylococcus lugdunensis</i> infective endocarditis: a multicentre international observational study.

Infectious diseases (London, England)·2025
Same journal

Accidental hypothermia.

Nature reviews. Disease primers·2026
Same journal

Accidental hypothermia.

Nature reviews. Disease primers·2026
Same journal

Primary aldosteronism.

Nature reviews. Disease primers·2026
Same journal

Primary aldosteronism.

Nature reviews. Disease primers·2026
Same journal

Buruli ulcer in Africa: between innovation and pragmatism.

Nature reviews. Disease primers·2026
Same journal

Author Correction: Atopic dermatitis.

Nature reviews. Disease primers·2026
See all related articles

Related Experiment Video

Updated: Mar 15, 2026

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

18.1K

Infective endocarditis.

Thomas L Holland1,2, Larry M Baddour3, Arnold S Bayer4

  • 1Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Room 185 Hanes Building, 315 Trent Drive, Durham, North Carolina 27710, USA.

Nature Reviews. Disease Primers
|September 2, 2016
PubMed
Summary
This summary is machine-generated.

Infective endocarditis (IE) is a serious heart infection that can affect many organs. Diagnosis and management require a multidisciplinary approach, and prevention strategies like vaccines are still under development.

More Related Videos

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

7.4K
Isolation of Valvular Endothelial Cells
11:04

Isolation of Valvular Endothelial Cells

Published on: December 29, 2010

21.1K

Related Experiment Videos

Last Updated: Mar 15, 2026

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

18.1K
An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

7.4K
Isolation of Valvular Endothelial Cells
11:04

Isolation of Valvular Endothelial Cells

Published on: December 29, 2010

21.1K

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Microbiology

Background:

  • Infective endocarditis (IE) is a rare but life-threatening condition with lasting effects.
  • It disproportionately impacts individuals with structural heart disease and healthcare-associated infections, especially those with prosthetic intravascular material.
  • IE involves complex interactions between pathogens and the host immune system, potentially affecting multiple organ systems.

Purpose of the Study:

  • To provide a comprehensive overview of infective endocarditis.
  • To discuss diagnostic challenges, particularly in blood culture-negative cases.
  • To highlight current management strategies and ongoing research in prevention.

Main Methods:

  • Review of existing literature and clinical guidelines.
  • Discussion of diagnostic criteria, including the modified Duke criteria.
  • Exploration of microbiological and imaging techniques for diagnosis.
  • Examination of multidisciplinary team management and prevention strategies.

Main Results:

  • IE diagnosis can be challenging, especially with negative blood cultures, necessitating advanced techniques.
  • The modified Duke criteria integrate clinical, microbiological, and echocardiographic findings for diagnosis.
  • Management requires a collaborative effort from infectious diseases, cardiology, and cardiac surgery specialists.

Conclusions:

  • Effective management of infective endocarditis relies on a multidisciplinary team approach.
  • Antibiotic prophylaxis for IE prevention remains a subject of debate.
  • Development of a commercially available vaccine for common bacterial causes of IE is still pending.