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Updated: Mar 15, 2026

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Supramolecular Assembly of Coronene Derivatives for Drug Delivery
Jie Yu1, Yong Chen1, Yu-Hui Zhang1
1Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University , Tianjin 300071, P. R. China.
Abstract:
Possessing a small size and C3-symmetrical rigid backbone, a coronene derivative was synthesized from β-cyclodextrins and hexa-cata-hexabenzocoronene, and then a water-soluble and biocompatible nanographene/polysaccharide supramolecular assembly was successfully fabricated through noncovalent interactions between adamantly grafted hyaluronic acids and β-cyclodextrin-modified hexa-cata-hexabenzocoronene. Moreover, the ternary supramolecular assembly showed not only a fluorescence imaging ability toward cancer cells but also good anticancer activity and low toxicity.
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