Related Experiment Video
Updated: Mar 15, 2026

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
Published on: March 28, 2017
Comparison of the Photoprotolytic Processes of Three 7-Hydroxycoumarins
Ron Simkovitch1, Luís Pinto da Silva, Joaquim C G Esteves da Silva
1Raymond and Beverly Sackler Faculty of Exact Sciences, School of Chemistry, Tel Aviv University , Tel Aviv 69978, Israel.
Abstract:
Steady-state and time-resolved fluorescence techniques, in addition to quantum mechanical calculations, were employed to study the excited-state proton transfer (ESPT) to solvent of three 7-hydroxycoumarin dyes. We found that for 7-hydroxycoumarins in water, the ESPT rate is high, about 2 × 1010 s-1, whereas in methanol the ESPT rate is much lower than that over the nonradiative lifetime of the excited singlet state; thus, the ESPT efficiency is very low.
More Related Videos
Related Concept Videos
Oxidation of Phenols to Quinones
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Drug Metabolism: Phase I Reactions
Phase I Reactions: Oxidation of Aliphatic and Aromatic Carbon-Containing Systems
Oxidation reactions are fundamental in aromatic carbon-containing systems. An example is the hydroxylation of phenobarbital, a process that transforms it into...

![Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F60786.jpg&w=3840&q=50)