Can a community-based multidisciplinary intervention effectively restore renal function? A non-randomized clinical...

Area of Science:

• Nephrology
• Public Health
• Preventive Medicine

Background:

• Limited evidence exists on lifestyle interventions for preventing renal dysfunction and promoting kidney regeneration.
• Chronic kidney disease (CKD) poses a significant global health burden.
• Early detection and intervention are crucial for managing kidney health.

Purpose of the Study:

• To evaluate the effectiveness of a community-based intervention program focused on lifestyle changes for renal restoration.
• To assess the impact of the "Healthy Kidney Program" on kidney function markers in at-risk patients.

Main Methods:

• A non-randomized clinical trial involving 120 patients with fractional excretion of magnesium (FEMg) levels >2% was conducted over six months.
• Participants were assigned to either an experimental group (lifestyle intervention) or a control group.
• The intervention included health education and personalized consultations with a multidisciplinary health team.

Main Results:

• The experimental group showed a significant decrease in FEMg levels within the six-month follow-up period.
• No significant changes in estimated glomerular filtration rate (eGFR) were observed in either the experimental or control groups.
• Screening for FEMg levels and the "Healthy Kidney Program" intervention demonstrated a positive effect on kidney health indicators.

Conclusions:

• Community-based lifestyle interventions can effectively reduce FEMg levels, indicating a potential role in preventing CKD progression.
• The "Healthy Kidney Program" shows promise as a strategy for early intervention and renal function preservation.
• Further research with randomized controlled trials is warranted to confirm these findings and explore long-term effects on eGFR.