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Related Experiment Video

Updated: Mar 15, 2026

Community-based Adapted Tango Dancing for Individuals with Parkinson's Disease and Older Adults

Community-based Adapted Tango Dancing for Individuals with Parkinson's Disease and Older Adults

Published on: December 9, 2014

And I hope you like jamming too.

Dhananjay T Tambe¹, Jeffrey J Fredberg²

¹Department of Mechanical Engineering, Department of Pharmacology and Center for Lung Biology, University of South Alabama, Mobile, AL 36688, USA.

New Journal of Physics

|September 6, 2016

Summary

Cell sorting, previously thought to follow fluid dynamics, deviates from energy minimization. Cancer cells may become kinetically trapped in solid-like states, challenging fluid tissue models.

Area of Science:

Biophysics
Cell Biology
Cancer Research

Background:

Cell sorting into tissues is often modeled as fluid immiscibility driven by surface tension.
Cellular properties like adhesion, stiffness, and contraction influence tissue surface tension.

Purpose of the Study:

To investigate the relationship between adhesion molecule density and cell-cell adhesion forces.
To determine if cancer cells behave as fluids in tissue sorting.

Main Methods:

Experimental analysis of cell-cell adhesion forces at interfaces.
Assessment of cancer cell behavior in tissue sorting contexts.

Main Results:

Adhesion forces did not correlate with adhesion molecule density as expected.

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Last Updated: Mar 15, 2026

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One-channel Cell-attached Patch-clamp Recording

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Published on: June 9, 2014

Dendrochronological Dating and Provenancing of String Instruments

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Published on: October 6, 2022

Certain cancer cell lines exhibited non-fluid, solid-like behavior, becoming kinetically trapped.

Conclusions:

Traditional fluid models of cell sorting may be insufficient, especially for cancer cells.
Cellular jamming in non-equilibrium states represents a novel mechanism in tissue organization.