Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Silicon Dioxide Multi-Mode Interference Spectrometers.

Micromachines·2026
Same author

Single molecule nanopore counting assay targeting small extracellular vesicle cargo for non-invasive monitoring of cerebral organoid development and health.

Scientific reports·2025
Same author

Universal Nanopore Sensor for Amplification-Free and Label-Free Detection of Molecular Biomarkers.

ACS sensors·2025
Same author

Air Core ARROW Waveguides Fabricated in a Membrane-Covered Trench.

Photonics·2025
Same author

Observational quality control study: insourcing multi-PCR-impact on the use of anti-infectives for patients with pleocytosis.

Neurological research and practice·2025
Same author

Process evaluation of a cross-sectoral, coordinated follow-up care of stroke patients: a qualitative study.

Neurological research and practice·2025
Same journal

Turbulent flow in a vortex separator with a directed pipe inlet.

Scientific reports·2026
Same journal

Systematic characteristic evaluation of clay-based cementitious material derived from calcium carbide residue and waste tile powder.

Scientific reports·2026
Same journal

Retraction Note: Improvement of a rapid diagnostic application of monoclonal antibodies against avian influenza H7 subtype virus using Europium nanoparticles.

Scientific reports·2026
Same journal

Applying large language models to spam detection in the Kazakh low-resource language setting.

Scientific reports·2026
Same journal

An open-source 3D printing system enabling in-situ freeze-thaw processing of hydrogels.

Scientific reports·2026
Same journal

An enhanced EfficientNet framework for automated waste classification using cosine annealing and label smoothing.

Scientific reports·2026
See all related articles

Related Experiment Video

Updated: Mar 15, 2026

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls
10:39

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls

Published on: April 12, 2018

7.8K

Flexible optofluidic waveguide platform with multi-dimensional reconfigurability.

Joshua W Parks1, Holger Schmidt1

  • 1School of Engineering, University of CA Santa Cruz, 1156 High Street, Santa Cruz, CA 95064 USA.

Scientific Reports
|September 7, 2016
PubMed
Summary
This summary is machine-generated.

This study presents a novel optofluidic platform combining solid- and liquid-core waveguides for dynamic optical tuning and high-performance microfluidic handling. It features a unique lightvalve for reconfigurable light and fluid paths, enabling advanced particle analysis.

More Related Videos

Author Spotlight: Developing a Unique Modular Microphysiological System to Mimic Human Barrier Tissue
06:20

Author Spotlight: Developing a Unique Modular Microphysiological System to Mimic Human Barrier Tissue

Published on: February 16, 2024

1.6K
Lensless Fluorescent Microscopy on a Chip
11:23

Lensless Fluorescent Microscopy on a Chip

Published on: August 17, 2011

18.3K

Related Experiment Videos

Last Updated: Mar 15, 2026

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls
10:39

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls

Published on: April 12, 2018

7.8K
Author Spotlight: Developing a Unique Modular Microphysiological System to Mimic Human Barrier Tissue
06:20

Author Spotlight: Developing a Unique Modular Microphysiological System to Mimic Human Barrier Tissue

Published on: February 16, 2024

1.6K
Lensless Fluorescent Microscopy on a Chip
11:23

Lensless Fluorescent Microscopy on a Chip

Published on: August 17, 2011

18.3K

Area of Science:

  • Optofluidics
  • Microfluidics
  • Photonics

Background:

  • Dynamic reconfiguration of photonic function is key in optofluidics.
  • Existing microfluidic devices lack simultaneous high-performance fluid handling and dynamic optical tuning.

Purpose of the Study:

  • Introduce a novel optofluidic platform enabling simultaneous microfluidic fluid handling and dynamic optical tuning.
  • Develop a device architecture for mechanically reconfigurable light and fluid paths.

Main Methods:

  • Utilized a combination of solid- and liquid-core polydimethylsiloxane (PDMS) waveguides.
  • Engineered a liquid-core multimode interference waveguide for tunable properties via core liquids and pressure/deformation.
  • Developed a novel lifting-gate lightvalve acting as both a microvalve and optical waveguide.

Main Results:

  • Demonstrated an optical switch with an extinction ratio exceeding 45 dB.
  • Showcased an actuatable particle trap for analyzing biological micro- and nanoparticles.
  • Achieved mechanically reconfigurable light and fluid paths.

Conclusions:

  • The developed platform integrates high-performance microfluidic handling with dynamic optical tuning.
  • The novel lightvalve enables precise control over light and fluid paths for particle analysis.
  • This architecture advances the capabilities of optofluidic devices for complex applications.