Related Experiment Video
Updated: Mar 15, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
[Ecthyma gangrenosum caused by Staphylococcus aureus].
Alejandra Jaque1, Catherina Moll-Manzur2, María Teresa Dossi3
1Departamento de Dermatología, Pontificia Universidad Católica de Chile, Chile, alejaque@gmail.com.
Ecthyma gangrenosum, a necrotizing vasculitis, typically stems from Pseudomonas aeruginosa sepsis in immunocompromised individuals. This case highlights methicillin-resistant Staphylococcus aureus as an unusual cause in a patient lacking typical risk factors.
Area of Science:
- Dermatology
- Infectious Diseases
- Pathology
Background:
- Ecthyma gangrenosum is a rare necrotizing vasculitis.
- It is most frequently associated with Pseudomonas aeruginosa sepsis.
- Immunocompromised patients are typically affected.
Observation:
- This report details an unusual case of ecthyma gangrenosum.
- The patient presented with methicillin-resistant Staphylococcus aureus infection.
- The patient lacked the classic immunological risk factors.
Findings:
- Methicillin-resistant Staphylococcus aureus can cause ecthyma gangrenosum.
- Ecthyma gangrenosum can occur in immunocompetent individuals.
- This broadens the spectrum of infectious etiologies for this condition.
Implications:
- Clinicians should consider a broader range of pathogens, including Staphylococcus aureus, in ecthyma gangrenosum.
- Further research is needed to understand the mechanisms of ecthyma gangrenosum in immunocompetent patients.
- This case expands the differential diagnosis for necrotizing skin lesions.
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Rheumatic Heart Disease I: Introduction
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Endocarditis I: Introduction
Myocarditis I: Introduction
