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Different Clinical Presentations of the Same Epidemic Keratoconjunctivitis Outbreak in Premature Babies and Their

Yusuf Koçluk1, Emine Alyamaç Sukgen1

  • 1a Department of Ophthalmology, Adana Numune Training and Research Hospital, Eye Department , Adana , Turkey.

Ocular Immunology and Inflammation
|September 7, 2016
PubMed

Insights

Premature babies with epidemic keratoconjunctivitis (EKC) showed no subepithelial corneal infiltrates (SEI). Adults in the same viral conjunctivitis outbreak had significantly more SEI after EKC.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Pediatrics

Background:

  • Epidemic keratoconjunctivitis (EKC) is a contagious viral eye infection.
  • Subepithelial corneal infiltrates (SEI) are a common complication of EKC, potentially affecting vision.
  • Premature infants may have unique responses to infections due to their immature immune systems.

Purpose of the Study:

  • To compare the clinical findings of EKC in premature infants versus adults during a viral conjunctivitis outbreak.
  • To specifically investigate the occurrence and differences in subepithelial corneal infiltrates (SEI) between these two groups.

Main Methods:

  • A prospective observational study design was employed.
  • Premature infants (n=25) and their affected family members (adults, n=30) diagnosed with EKC were monitored.
  • Patients were categorized into two groups: preterm babies (Group 1) and adults (Group 2).

Main Results:

  • Subepithelial corneal infiltrates (SEI) were assessed at 2 weeks, 1 month, and 3 months post-EKC diagnosis.
  • A statistically significant difference in SEI distribution was observed between the two groups at all follow-up visits (p<0.0001).
  • Adults (Group 2) exhibited a higher incidence of SEI compared to premature infants (Group 1).

Conclusions:

  • None of the premature infants in the study developed subepithelial corneal infiltrates (SEI) following EKC.
  • This suggests a potentially different or milder course of EKC regarding corneal complications in preterm neonates compared to adults.
Abstract

Keywords:
Epidemic keratoconjunctivitisfamily membersoutbreak of viral conjunctivitispremature babiessubepithelial corneal infiltrates

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