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Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
Vanessa G Alves1, Alan G Souza1, Lucas U R Chiavelli1
1Universidade Estadual de Maringá/UEM, Departamento de Química, Avenida Colombo, 5790, 87020-900 Maringá, PR, Brasil.
Abstract:
The cultivation of sugarcane hybrids (X Saccharum officinarum L.) is an important revenue source for the Brazilian economy. Herein it is reported the evaluation of the cytotoxic activity of mid-polarity sugarcane extracts against human cancer cell lines, as well as the isolation of steroids sitosterol, stigmasterol and campesterol, phenolic acids p-hydroxybenzoic, p-hydroxycinnamic, vanillic and ferulic acid, terpenoids α-tocopherol and β-carotene and a novel substance in sugarcane, the flavonoid aglycone tricin (5,7,4-trihydroxy-3,5-dimethoxyflavone). The presence of large amounts of phenolic acids and the flavonoid tricin may explain the cytostatic activity observed for the mid-polarity crude extract and filtrates.
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