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PIPc study: development of indicators of potentially inappropriate prescribing in children (PIPc) in primary care

Emma Barry1, Kirsty O'Brien1, Frank Moriarty1

  • 1Department of General Practice, HRB Centre for Primary Care Research, Royal College of Surgeons in Ireland, Dublin, Ireland.

BMJ Open
|September 8, 2016
PubMed

Insights

Researchers developed 12 prescribing indicators to assess potentially inappropriate prescribing in children (PIPc) within primary care. These indicators will help evaluate pediatric medication safety using prescribing databases.

Area of Science:

  • Pediatric Pharmacology
  • Health Services Research
  • Medication Safety

Background:

  • Limited evidence exists on prescribing quality for pediatric populations in primary care.
  • Existing prescribing indicators are primarily designed for adult populations, lacking relevance for children.

Purpose of the Study:

  • To develop a validated set of prescribing indicators for assessing potentially inappropriate prescribing in children (PIPc).
  • To create criteria applicable to prescribing or dispensing data sets for pediatric primary care.

Main Methods:

  • A two-round modified Delphi consensus method was employed.
  • A panel of 15 experts (GPs, pharmacists, pediatricians) from Irish and UK general practices participated.
  • Indicators were refined through literature review, clinical expertise, and expert feedback.

Main Results:

  • Initially, 47 indicators were reviewed, with 16 presented to the Delphi panel.
  • Consensus was reached on 12 final indicators after two rounds of Delphi process.
  • The final indicators are categorized by system: respiratory (6), gastrointestinal (2), neurological (2), and dermatological (2).

Conclusions:

  • The developed PIPc indicators provide criteria for assessing pediatric prescribing in primary care, especially when clinical data is absent.
  • Further studies are planned to test the utility of these indicators using prescribing databases.
Abstract

Keywords:
Delphi methodchildrenexplicit criteriapotentially inappropriate prescribingprescribing indicators

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