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Updated: Mar 15, 2026

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

Study on lumbosacral nerve root compression using DTI.

Jinfeng Li¹, Yonghao Wang², Yueyi Wang³

¹Department of Radiology, Chinese People Liberation Army (PLA) General Hospital, Beijing 100853, P.R. China.

Biomedical Reports

|September 8, 2016

Summary

This summary is machine-generated.

Diffusion tensor imaging (DTI) reveals significant differences in nerve root compression. Lower apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values in compressed nerve roots indicate DTI

Keywords:

apparent diffusion coefficient degeneration diffusion tensor imaging fractional anisotropy lumbar intervertebral disc

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Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Area of Science:

Medical Imaging
Neuroscience
Radiology

Background:

Lumbar intervertebral disc degeneration frequently causes lumbosacral nerve root compression.
Objective quantitative assessment of nerve root injury is crucial for diagnosis and treatment planning.

Purpose of the Study:

To evaluate the diagnostic value of diffusion tensor imaging (DTI) in assessing lumbosacral nerve root compression.
To investigate quantitative indicators of nerve root injury using DTI in patients with lumbar disc degeneration.

Main Methods:

Diffusion tensor imaging (DTI) was performed on 45 patients with lumbar intervertebral disc degeneration.
Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values were measured in compressed and uncompressed nerve roots.
Fiber tracking imaging was utilized to visualize lumbosacral nerve roots.

Main Results:

Compressed nerve roots showed significantly lower ADC values (1.314±0.14 mm²/sec) compared to uncompressed roots (1.794±0.11 mm²/sec) (P<0.05).
Compressed nerve roots exhibited significantly lower FA values (0.196±0.020) than uncompressed roots (0.272±0.016) (P<0.05).
DTI effectively visualized and differentiated between compressed and normal lumbosacral nerve roots.

Conclusions:

Diffusion tensor imaging (DTI) can objectively identify and quantify lumbosacral nerve root compression.
DTI provides valuable quantitative data (ADC and FA values) for assessing nerve root injury in lumbar disc degeneration.
DTI is a promising tool for evaluating lumbosacral nerve root damage in clinical practice.