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GAG mimetic functionalised solid and mesoporous silica nanoparticles as viral entry inhibitors of herpes simplex type
Edward C Lee1, Nicholas Davis-Poynter, Chau T H Nguyen
1The University of Queensland, School of Pharmacy, Brisbane, QLD 4072, Australia. b.ross1@uq.edu.au a.popat@uq.edu.au.
Nanoscale
|September 9, 2016
Abstract:
A glycosaminoglycan mimetic was attached to the surface of solid and mesoporous silica nanoparticles to create novel antiviral agents against herpes simplex type 1 and type 2 viruses. The nanoparticles act as viral entry inhibitors that appear to block viral attachment and penetration into susceptible cells.
