Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pregnancy and epilepsy.

S Bag1, M Behari, G K Ahuja

  • 1Department of Neurology, All India Institute of Medical Sciences, New Delhi.

Journal of Neurology
|July 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of Cryopreservation on Semen Quality Parameters in Relation to Lipid Peroxidation and Antioxidant Profile in Indian Buffalo.

Cryo letters·2021
Same author

Expression and functional role of IGFs during early pregnancy in placenta of water buffalo.

Theriogenology·2020
Same author

Expression and functional role of fibroblast growth factors (FGF) in placenta during different stages of pregnancy in water buffalo (Bubalus bubalis).

Theriogenology·2019
Same author

Flaxseed oil modulates semen production and its quality profiles, freezability, testicular biometrics and endocrinological profiles in mithun.

Theriogenology·2019
Same author

Expression and functional role of kisspeptin and its receptor in the cyclic corpus luteum of buffalo (Bubalus bubalis).

Theriogenology·2019
Same author

Natural Infection of Iris yellow spot virus in Twoscale Saltbush (Atriplex micrantha) Growing in Utah.

Plant disease·2019
Same journal

Genome-wide spectrum of coding DNA variations in Indian patients with amyotrophic lateral sclerosis.

Journal of neurology·2026
Same journal

Number needed to treat and harm for lecanemab and donanemab in early Alzheimer disease.

Journal of neurology·2026
Same journal

Genetic spectrum and clinical features of PMP22 point mutations in Japanese Charcot-Marie-Tooth disease.

Journal of neurology·2026
Same journal

Migraine and auditory dysfunction: beyond comorbidity.

Journal of neurology·2026
Same journal

Efficacy and safety of ofatumumab in participants with relapsing multiple sclerosis and breakthrough disease on oral fingolimod or fumarates: results from the ARTIOS study.

Journal of neurology·2026
Same journal

Triple-crush mechanism in multiple sclerosis-associated trigeminal neuralgia.

Journal of neurology·2026
See all related articles

Pregnancy impacts epilepsy, with hormonal changes affecting seizure frequency. Elevated estrogen levels correlated with increased seizures, abortions, and status epilepticus in pregnant epileptic patients.

Area of Science:

  • Obstetrics and Gynecology
  • Neurology
  • Pharmacology

Background:

  • Epilepsy affects pregnant individuals, necessitating understanding of its impact on both maternal health and fetal development.
  • Hormonal fluctuations during pregnancy can influence seizure activity in epileptic patients.

Purpose of the Study:

  • To investigate the bidirectional effects of pregnancy on seizure frequency in epileptic patients.
  • To correlate serum hormone levels and anticonvulsant drug concentrations with seizure occurrence, pregnancy complications, and teratogenicity.

Main Methods:

  • Prospective study of 30 pregnant epileptic patients throughout their gestation.
  • Monitoring of seizure frequency, pregnancy complications, and serum levels of hormones and anticonvulsant medications.

Related Experiment Videos

Main Results:

  • Seizure frequency increased in 14 patients, remained unchanged in 15, and decreased in 1.
  • Two spontaneous abortions and two cases of status epilepticus occurred.
  • One infant had a ventricular septal defect; this patient received carbamazepine and diphenylhydantoin.
  • Increased seizure frequency was associated with higher estrogen, lower progesterone, and lower anticonvulsant drug levels.
  • High serum estrogen levels were observed in patients experiencing abortions or status epilepticus.

Conclusions:

  • Pregnancy significantly influences seizure control in epileptic individuals, with hormonal shifts playing a crucial role.
  • Elevated estrogen levels appear to be a risk factor for increased seizure frequency, spontaneous abortions, and status epilepticus during pregnancy.
  • Monitoring hormone and drug levels is essential for managing epilepsy in pregnant patients.