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Related Concept Videos

Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

1.6K
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
1.6K
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

2.2K
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
2.2K
IR Spectroscopy: Molecular Vibration Overview01:24

IR Spectroscopy: Molecular Vibration Overview

5.7K
When Infrared (IR) radiation passes through a covalently bonded molecule, the bonds transition from lower to higher vibrational levels. The fundamental vibrational motions that result in infrared absorption can be classified as stretching or bending vibrations.
Stretching vibrations are vibrational motions that occur along the bond line, changing the bond length or distance between two bonded atoms. They are further distinguished as symmetric or asymmetric. In symmetric stretching, the...
5.7K
IR Spectroscopy: Hooke's Law Approximation of Molecular Vibration01:16

IR Spectroscopy: Hooke's Law Approximation of Molecular Vibration

3.4K
A covalently bonded heteronuclear diatomic molecule can be modeled as two vibrating masses connected by a spring. The vibrational frequency of the bond can be expressed using an equation derived from Hooke's law, which describes how the force applied to stretch or compress a spring is proportional to the displacement of the spring. In this case, the atoms behave like masses, and the bond acts like a spring.
According to Hooke's law, the vibrational frequency is directly proportional to...
3.4K
Spectroscopy of Carboxylic Acid Derivatives01:26

Spectroscopy of Carboxylic Acid Derivatives

3.2K
Infrared spectroscopy is primarily used to determine the types of bonds and functional groups. In carboxylic acid derivatives, a typical carbonyl bond absorption is observed around 1650–1850 cm−1. For esters, the absorption is recorded at around 1740 cm−1, while acid halides show the absorption at about 1800 cm−1. Another acid derivative, the acid anhydrides, exhibit two carbonyl absorption around 1760 cm−1 and 1820 cm−1, arising from the symmetrical and...
3.2K
¹H NMR of Conformationally Flexible Molecules: Temporal Resolution00:52

¹H NMR of Conformationally Flexible Molecules: Temporal Resolution

1.4K
At room temperature, the chair conformer of cyclohexane undergoes rapid ring flipping between two equivalent chair conformers at a rate of approximately 105 times per second. These two chair conformers are in equilibrium. The rapid ring flipping results in the interconversion of the axial proton to an equatorial proton and an equatorial to the axial proton. Such interconversions are too rapid and cannot be detected on the NMR timescale. Hence, the NMR spectrometer cannot distinguish between the...
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Updated: Mar 15, 2026

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems
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Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems

Published on: February 10, 2020

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Time-domain Raman analytical forward solvers.

Fabrizio Martelli, Tiziano Binzoni, Sanathana Konugolu Venkata Sekar

    Optics Express
    |September 9, 2016
    PubMed
    Summary
    This summary is machine-generated.

    New analytical solvers accurately model time-domain Raman signals in diffusive media, accounting for background fluorescence. These tools enhance the analysis of time-resolved Raman measurements for various geometries.

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    Area of Science:

    • Biomedical Optics
    • Spectroscopy
    • Mathematical Modeling

    Background:

    • Raman spectroscopy is a valuable technique for chemical analysis.
    • Accurate modeling of Raman signals in diffusive media is crucial for quantitative analysis.
    • Background fluorescence can interfere with Raman signal detection.

    Purpose of the Study:

    • To develop time-domain analytical forward solvers for Raman signals in homogeneous diffusive media.
    • To incorporate background fluorescence into the solvers.
    • To validate the developed solvers against established methods.

    Main Methods:

    • Solving the time-dependent diffusion equation for two geometries: parallelepiped and finite cylinder.
    • Developing analytical forward solvers for Raman signal detection.
    • Comparing solver results with Monte Carlo simulations.

    Main Results:

    • A set of validated time-domain analytical forward solvers for Raman signals was created.
    • The solvers accurately model Raman signals in both parallelepiped and finite cylinder geometries.
    • The influence of background fluorescence on Raman signals was successfully accounted for.

    Conclusions:

    • The developed time-domain solvers offer an accurate computational tool for analyzing Raman signals.
    • These solvers facilitate the exploration of information within time-resolved Raman measurements.
    • The methodology provides a robust approach for studying diffusive media using Raman spectroscopy.