In-vivo optical properties spectra across five body locations on ten subjects using time-domain diffuse optics

Area of Science:

• Biomedical Optics
• Medical Imaging
• Data Science

Background:

• Diffuse optical spectroscopy (DOS) is a non-invasive imaging technique.
• Understanding tissue optical properties is crucial for developing DOS applications.
• Inter-subject and inter-site variability in optical properties is a known challenge.

Purpose of the Study:

• To present a comprehensive, openly available dataset of absorption and reduced scattering spectra.
• To include corresponding ultrasound images and demographic information to aid in analyzing variability.
• To facilitate the development of light-based diagnostic and therapeutic techniques.

Main Methods:

• Collected time-domain diffuse optical spectroscopy (TD-DOS) data in the 610-1110 nm range.
• Acquired ultrasound images concurrently with optical measurements.
• Gathered data from 10 subjects across 5 distinct body locations (upper arm, radius-ulna, abdomen, forehead, calcaneus).

Main Results:

• A comprehensive dataset including raw optical spectra, reduced scattering spectra, ultrasound images, and demographic data was compiled.
• The dataset provides insights into inter-subject variability in optical properties.
• The data spans a wide spectral range relevant for various tissue types.

Conclusions:

• The openly available dataset supports research in biomedical optics and photon migration modeling.
• This resource can accelerate the development of novel light-based diagnostic and therapeutic tools.
• The inclusion of multimodal data (optical and ultrasound) enhances its utility for studying biological variability.