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Neuroretinitis in childhood
1Department of Ophthalmology, College of Medicine, University of South Florida, Tampa 33612-4799.
Insights
This study details neuroretinitis in seven children, noting varied disc swelling and persistent macular exudates. Some patients experienced permanent vision loss, with cat-scratch disease identified in two cases.
Area of Science:
- Ophthalmology
- Pediatric Neurology
Background:
- Neuroretinitis is an inflammatory condition affecting the optic nerve and retina.
- Diagnosis relies on visual acuity, pupillary response, and funduscopic findings.
Observation:
- Seven children with neuroretinitis were studied.
- Clinical features included reduced visual acuity and pupillary defects.
- Funduscopic examination revealed segmental or diffuse disc swelling and transient retinal infiltrates.
Findings:
- Optic disc and peripapillary swelling, with vitritis, resolved within 2-6 weeks.
- Macular exudates persisted for 3-12 months.
- Two patients developed optic atrophy and permanent vision loss; two had reduced visual acuity under low contrast.
Implications:
- Neuroretinitis can lead to significant visual impairment, including permanent vision loss.
- Early diagnosis and management are crucial in pediatric cases.
- Cat-scratch disease is a potential, but not the sole, cause of pediatric neuroretinitis.
Abstract:
We report the clinical features and results of laboratory testing of seven children with neuroretinitis, diagnosed on the basis of reduced visual acuity, relative afferent pupillary defect, and distinctive appearance of the fundi. Disc swelling was segmental in five patients with unilateral disease and diffuse in two patients with bilateral disease. Retinal infiltrates were transiently present in two patients. Swelling of the optic disc and peripapillary retina, along with the inflammatory vitritis resolved by 2 to 6 weeks but macular exudates persisted for 3 to 12 months. Two patients developed optic atrophy with permanent visual loss and two patients had visual acuity reduction detected only under low contrast conditions. Cat-scratch disease was implicated as the cause of the neuroretinitis in two patients; the etiology of the remaining cases was not established.
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