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Use of Old World monkeys for acquired immunodeficiency syndrome research
I Nicol1, D Messinger, P Dubouch
1Laboratoire de Physiologie Cellulaire, Université Pierre et Marie Curie, Paris, France.
Journal of Medical Primatology
|January 1, 1989
Abstract:
Mangabeys, macaques, and baboons persistently infected with human immunodeficiency virus (HIV)-2 NIH-DZ demonstrated no signs of immunodeficiency disease after 6-11 months following seroconversion. Thus Old World monkeys provide an animal model to investigate the effects of passive immunization (anti-HIV-2 antibodies) on HIV infection in primates.