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Pediatric Obsessive-Compulsive Disorder Exacerbation and Obstructive Hydrocephalus: A Case Report
Aldrich Leung1, Clare Bleakley2, Adrian Loh1,2
1Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Pediatrics
|September 10, 2016
Summary
A boy
Area of Science:
- Neuroscience
- Pediatric Neurology
- Psychiatry
Background:
- Obsessive-compulsive disorder (OCD) is a complex neuropsychiatric condition.
- The etiology of OCD is thought to involve dysfunction in cortico-striatal-thalamic-cortical (CSTC) pathways.
Observation:
- An 11-year-old boy with a history of OCD experienced acute symptom exacerbation.
- This worsening coincided with obstructive hydrocephalus caused by a tectal low-grade glioma.
Findings:
- Resolution of hydrocephalus through management led to improvement in OCD compulsion symptoms.
- This case suggests a potential link between structural brain changes and OCD symptom severity.
Implications:
- Highlights the importance of neurological evaluation for acute OCD exacerbations, especially with concurrent neurological signs.
- Suggests that structural brain abnormalities, even subtle ones, may influence OCD pathophysiology and treatment response.
- Emphasizes considering neurological causes in the differential diagnosis of severe OCD flares.
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