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Updated: Mar 15, 2026

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography
Published on: January 11, 2020
Fluorine-18 patents (2009-2015). Part 2: new radiochemistry
Andrew V Mossine1, Stephen Thompson1, Allen F Brooks1
1Department of Radiology, University of Michigan Medical School, 1301 Catherine St., Ann Arbor, MI 48109, USA.
Abstract:
Fluorine-18 ((18)F) is one of the most common positron-emitting radionuclides used in the synthesis of positron emission tomography radiotracers due to its ready availability, convenient half-life and outstanding imaging properties. In Part 1 of this review, we presented the first analysis of patents issued for novel radiotracers labeled with fluorine-18. In Part 2, we follow-up with a focus on patents issued for new radiochemistry methodology using fluorine-18 issued between January 2009 and December 2015.
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