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A whole-molecule immunocapture LC-MS approach for the in vivo quantitation of biotherapeutics

John F Kellie1, Jonathan R Kehler1, Thomas J Mencken1

  • 1Bioanalysis, Immunogenicity & Biomarkers, In vitro/In vivo Translation Platform, R&D Platform Technology & Science, GSK, 709 Swedeland Road, King of Prussia, PA 19406, USA.

Bioanalysis
|September 10, 2016
PubMed
Abstract

Keywords:
biotherapeutic quantitationimmunoassay LC–MSimmunocapture LC–MSintact protein quantitationtop-down MSwhole-molecule MS

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