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Systemic and inflammatory disorders involving the heart: the role of PET imaging

Daniel Juneau1, Fernanda Erthal, Atif Alzahrani

  • 1Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Canada - bchow@ottawaheart.ca.

The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [And] the International Association of Radiopharmacology (IAR), [And] Section of the Society Of
|September 10, 2016
PubMed

Insights

Positron emission tomography (PET) imaging, particularly with Fluorine-18 fluorodeoxyglucose (FDG), aids in diagnosing challenging cardiac inflammatory disorders. This metabolic imaging offers advantages over anatomical methods, especially when standard tests are inconclusive.

Area of Science:

  • Cardiology
  • Nuclear Medicine
  • Medical Imaging

Background:

  • Cardiac inflammatory disorders present diagnostic challenges due to overlapping symptoms with other cardiac conditions.
  • Accurate diagnosis is crucial as these disorders are associated with significant morbidity and mortality.

Purpose of the Study:

  • To evaluate the diagnostic utility of positron emission tomography (PET) imaging in cardiac inflammatory disorders.
  • To highlight the role of Fluorine-18 fluorodeoxyglucose (FDG) PET in assessing various cardiac inflammatory conditions.

Main Methods:

  • Review of recent publications investigating PET imaging in cardiac inflammatory disorders.
  • Focus on the application of Fluorine-18 fluorodeoxyglucose (FDG) tracer in diagnosing conditions like myocarditis, pericarditis, and endocarditis.

Main Results:

  • PET imaging, especially FDG-PET, shows promise in diagnosing cardiac inflammation.
  • It can detect metabolic changes preceding anatomical alterations, offering an advantage over conventional imaging.
  • PET is particularly useful in non-diagnostic or equivocal cases.

Conclusions:

  • PET imaging, utilizing tracers like FDG, is a valuable tool for the diagnosis, prognosis, and follow-up of cardiac inflammatory disorders.
  • Its ability to visualize metabolic activity makes it advantageous in complex cardiac cases where standard investigations are insufficient.

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