Related Experiment Videos
[Acute psychosis caused by poisoning with cyclopentolate]
Klinische Monatsblatter Fur Augenheilkunde
|June 1, 1989
Summary
Cyclopentolate eye drops can cause psychotic attacks, even in young patients. While rare, systemic toxicity is possible across all ages, highlighting the need for careful administration.
Area of Science:
- Ophthalmology
- Pharmacology
- Psychiatry
Background:
- Cyclopentolate is commonly used for diagnostic eye examinations.
- Systemic side effects of topical cyclopentolate are rare but documented.
Observation:
- A 17-year-old female experienced an acute psychotic attack following the local application of 1.0% cyclopentolate in both eyes.
Findings:
- Systemic toxicity from cyclopentolate can occur in any age group, irrespective of prior tolerance.
- Toxicity is not specific to patients with pre-existing neurological or psychiatric conditions.
Implications:
- Despite rare systemic toxicity, cyclopentolate remains a valuable diagnostic agent due to its rapid and short-lived cycloplegic effects.
- Clinicians should be aware of potential systemic side effects, including psychiatric reactions, even with topical administration.