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Genomics02:02

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

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Establishment of a Clinic-based Biorepository
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Population-based imaging biobanks as source of big data.

Sergios Gatidis1, Sophia D Heber1, Corinna Storz1

  • 1Department of Radiology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.

La Radiologia Medica
|September 11, 2016
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Summary

Computational advances enable big data in biomedical research, particularly in medical imaging for identifying biomarkers. This review discusses population imaging studies, their opportunities, and challenges in the big data era.

Keywords:
Big dataEpidemiologyImagingMRI

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Area of Science:

  • Biomedical Research
  • Computational Science
  • Medical Imaging

Background:

  • Computational science advances enable novel biomedical research methods.
  • Big data approaches extract significant information from extensive research data.
  • Medical imaging is increasingly used in epidemiological studies.

Purpose of the Study:

  • Present existing epidemiological imaging studies.
  • Discuss opportunities in population imaging.
  • Address methodological, organizational, and challenges of big data in population imaging.

Main Methods:

  • Review of epidemiological imaging studies.
  • Analysis of big data methodologies in medical imaging.
  • Discussion of challenges and opportunities in population imaging research.

Main Results:

  • Epidemiological studies utilize advanced imaging to identify biomarkers.
  • Imaging biomarkers provide insights into physiological and pathological processes.
  • Population imaging presents unique big data challenges and opportunities.

Conclusions:

  • Population imaging is a growing field within big data research.
  • Methodological and organizational aspects require careful consideration.
  • Future research should address the challenges for successful implementation.