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Updated: Mar 15, 2026

A Multiplexed Luciferase-based Screening Platform for Interrogating Cancer-associated Signal Transduction in Cultured Cells
Published on: July 3, 2013
[Does a cancer moonshot make sense?]
1UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS, Espace éthique méditerranéen, hôpital d'adultes la Timone, 264, rue Saint-Pierre, 13385 Marseille Cedex 05, France.
Abstract:
The recently announced "Cancer moonshot" may be greeted with scepticism: the previous "War on cancer" (1971) was not very successful. However the current plan seems well targeted, with emphasis not only on research investment but also on a strong effort to "break down silos" and ensure wide dissemination and use of clinical and molecular data. One big uncertainty, however, is what will happen to the programme after the 2016 presidential election… ‡.
Insights
The Cancer Moonshot initiative aims to accelerate cancer research and data sharing, building on lessons from the past. Its long-term success faces uncertainty beyond the current political administration.
Area of Science:
- Oncology
- Public Health Policy
- Biomedical Research
Background:
- The prior "War on Cancer" initiated in 1971 yielded limited success.
- Recent advancements in molecular biology and data science offer new opportunities for cancer research.
Purpose of the Study:
- To evaluate the strategic approach of the Cancer Moonshot initiative.
- To identify key components for successful cancer research and data dissemination.
Main Methods:
- Analysis of the Cancer Moonshot's stated goals and strategies.
- Comparison with historical cancer research initiatives.
- Assessment of potential barriers to implementation and sustainability.
Main Results:
- The Cancer Moonshot emphasizes research funding and interdisciplinary collaboration.
- A key focus is on breaking down silos and promoting data sharing.
- The program's future beyond the 2016 election remains a significant uncertainty.
Conclusions:
- The Cancer Moonshot's targeted approach, focusing on data integration and collaboration, shows promise.
- Sustained political will and funding are critical for its long-term impact.
- Addressing the program's long-term viability is essential for achieving its ambitious goals.
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