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Related Concept Videos

Acute Pharyngitis01:30

Acute Pharyngitis

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Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
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Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

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In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
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Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Hypersensitivity Reactions: Cytolytic Reactions01:01

Hypersensitivity Reactions: Cytolytic Reactions

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Type II hypersensitivity involves IgG and IgM antibodies targeting cell surface antigens, leading to cell destruction. This can occur through complement activation, antibody-dependent cell-mediated cytotoxicity (ADCC), or acting as opsonins for phagocytosis. When excessive, these reactions cause significant tissue damage.Drug-induced hemolytic anemia is a common example, where drugs like penicillin or cephalosporins bind to red blood cells, forming drug-protein complexes. These complexes...
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Vaccinations01:51

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Related Experiment Video

Updated: Mar 15, 2026

Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
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Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation

Published on: July 9, 2014

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Herpes zoster in children.

Nathan Peterson1, Seth Goodman2, Michael Peterson3

  • 1Arizona Desert Dermatology, Kingman, USA.

Cutis
|September 14, 2016
PubMed
Summary

Herpes zoster (HZ) is rare in children. This case shows HZ can occur in immunocompetent children after varicella vaccination, highlighting the need for awareness.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Immunology

Background:

  • Herpes zoster (HZ) is uncommon in immunocompetent children.
  • Varicella-zoster virus (VZV) exposure can be from wild-type or vaccine strains.
  • VZV infection can lead to latent infection and subsequent HZ.

Observation:

  • A 15-month-old boy developed HZ.
  • The child received the varicella vaccine at 12 months of age.
  • This case is rare in immunocompetent children.

Findings:

  • Presents a case of HZ in a young child post-varicella vaccination.
  • Reviews the incidence, clinical characteristics, and diagnosis of HZ in children.
  • Suggests vaccine-related VZV strains can cause HZ.

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A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
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Related Experiment Videos

Last Updated: Mar 15, 2026

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Implications:

  • Highlights the importance of considering HZ in vaccinated children presenting with a rash.
  • Informs clinical diagnosis and management of pediatric HZ.
  • Contributes to understanding VZV epidemiology post-vaccination.