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Updated: Mar 15, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
[The choice of surgery in patients with diffuse toxic goiter]
A N Vachev1, E V Frolova1, D R Sakhipov1
1Department and Clinic of Faculty Surgery, Samara State Medical University, Ministry of Health of the Russian Federation, Russia.
Aim:
to define clear individual indications for different operations for diffuse toxic goiter by research of immunological markers of thyrotoxicosis recurrence probability.
Material And Methods:
Long-term results of survey and treatment of 215 patients with diffuse toxic goiter are presented. Patients were divided into 2 groups. The 1st group consisted of 31 patienrs who underwent conventional partial thyroidectomy. Group 2 included 184 patients. They were divided into 2 subgroups depending on type of surgery. Subgroup A included 59 patients after partial thyroidectomy and subgroup B - 125 patients after total thyroidectomy. In group 2 surgery was defined based on only level of antibodies against TSH-receptors.
Results:
Recurrence incidence was 16 and 0% in groups 1 and 2 respectively.
Conclusion:
In patients with diffuse toxic goiter partial thyroidectomy is possible if normal titer of antibodies against TSH-receptors is present (<1.5 U/l). Total thyroidectomy is advisable in titer ≥1.5 U/l.
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