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Updated: Mar 15, 2026
Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics
Published on: May 11, 2016
Fallacious Carcinoma- Spindle Cell Variant of Squamous Cell Carcinoma
Radhika M Bavle1, Girish Govinda2, Padmalatha Gundappanayakanahalli Venkataramanaiah3
1Professor and Head, Department of Oral Pathology, Krishnadevaraya College of Dental Sciences , Bangalore, Karnataka, India .
Abstract:
Spindle cell carcinoma is a unique, rare and peculiar biphasic tumour of head and neck which is not frequently observed in the oral cavity. This variant of squamous cell carcinoma although of monophasic epithelial origin, simulates a sarcoma and is an aggressive carcinoma with high frequency of recurrence and metastasis. A correct and timely diagnosis is of paramount importance. Most of the tumours require an Immunohistochemistry (IHC) panel for confirmation or diagnosis. We report a case of spindle cell carcinoma with varied histopathological morphology and clinical presentation in a middle aged female with a brief review of literature.
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