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Updated: Mar 15, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
A new edge to immune surveillance by the neural system
Jochem H Bernink1, Hergen Spits1, Wouter J de Jonge2
1Department of Experimental Immunology, Academic Medical Center at the University of Amsterdam, Amsterdam, the Netherlands.
Abstract:
A recent paper published in Nature demonstrates a multifaceted relation between enteric glial cells (EGC), intestinal epithelia, and ILC3, via the EGC release of neurotrophic factors, a structurally related group of ligands within the TGF-β superfamily of signaling molecules and IL-22 produced by ILC3.
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