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Updated: Mar 15, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Contemporary Imaging in Takotsubo Syndrome
Rodolfo Citro1, Gianluca Pontone2, Leonardo Pace3
1Department of Cardiology, University Hospital "San Giovanni di Dio e Ruggi d'Aragona," Heart Tower Room 810, Largo Città di Ippocrate, Salerno 84131, Italy.
Transthoracic echocardiography is key for diagnosing Takotsubo syndrome (TTS) and managing complications. Advanced imaging like cardiac MRI and CT angiography aid in diagnosis and risk assessment for TTS patients.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Takotsubo syndrome (TTS) presents diagnostic challenges.
- Effective risk stratification and management are crucial for TTS patients, especially those with cardiogenic shock.
Purpose of the Study:
- To outline the role of various imaging modalities in the evaluation of Takotsubo syndrome.
- To highlight the utility of these techniques in diagnosis, complication detection, risk stratification, and differential diagnosis.
Main Methods:
- Transthoracic echocardiography (TTE) as the primary diagnostic tool.
- Cardiac magnetic resonance (CMR) for detecting myocardial edema and differential diagnosis.
- Coronary computed tomography angiography (CCTA) as an alternative to coronary angiography.
- Molecular imaging for assessing recurrence risk.
Main Results:
- TTE is the first-line imaging modality for TTS diagnosis and management.
- CMR aids in identifying myocardial edema and differentiating TTS from other conditions.
- CCTA can confirm coronary artery patency, serving as an alternative to invasive angiography.
- Molecular imaging shows potential for predicting TTS recurrence.
Conclusions:
- A multimodal imaging approach is essential for comprehensive Takotsubo syndrome evaluation.
- Advanced imaging techniques enhance diagnostic accuracy, risk stratification, and patient management in TTS.
- Future research in molecular imaging may improve prediction of TTS recurrence.
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