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Resistance-based interval exercise acutely improves endothelial function in type 2 diabetes.

Monique E Francois1, Cody Durrer1, Kevin J Pistawka2

  • 1School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, British Columbia, Canada; and.

American Journal of Physiology. Heart and Circulatory Physiology
|September 18, 2016
PubMed
Summary
This summary is machine-generated.

Resistance interval exercise acutely improves endothelial function in type 2 diabetes patients for up to two hours post-exercise. This study highlights the benefits of interval training for vascular health in this population.

Keywords:
HIITblood flowblood pressureflow-mediated dilationhigh-intensity interval exercisehigh-intensity interval trainingstrength trainingvascular function

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Area of Science:

  • Exercise Physiology
  • Cardiovascular Health
  • Metabolic Disease

Background:

  • Exercise type and training status influence endothelial shear stress and function.
  • The acute endothelial response to interval exercise in type 2 diabetes (T2D) and varying training statuses is not well understood.

Purpose of the Study:

  • To investigate the acute effects of resistance interval (R-INT) and cardio interval (C-INT) exercise on endothelial function in individuals with T2D, untrained, and trained adults.
  • To compare these effects against a time-matched seated control (CTL).

Main Methods:

  • 12 T2D patients, 12 untrained, and 11 trained adults (mean age 56 ± 7 yr) participated.
  • Participants underwent randomized, separated sessions of R-INT, C-INT, and CTL.
  • Endothelial function, measured as brachial artery flow-mediated dilation (%FMD), was assessed at baseline and 0, 1, and 2 hours post-intervention.

Main Results:

  • R-INT significantly improved %FMD in all groups, with the most pronounced effect observed in the T2D group immediately, 1-hour, and 2-hours post-exercise compared to CTL.
  • C-INT demonstrated a significant improvement in %FMD in the T2D group at 1-hour post-exercise compared to CTL.
  • No significant improvements were noted for the control condition across any group.

Conclusions:

  • Resistance interval training acutely enhances endothelial function in type 2 diabetes patients for at least two hours post-exercise.
  • Further research into the long-term effects of interval-style resistance training is warranted for T2D management.