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MANTA, a novel plug-based vascular closure device for large bore arteriotomies: technical report
Lennart van Gils1, Joost Daemen, Greg Walters
1Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
Summary
Large arteriotomy closure after cardiovascular interventions can be challenging. The novel MANTA vascular closure device (VCD) offers a percutaneous collagen-based solution for large arteriotomies, potentially reducing complications.
Area of Science:
- Cardiovascular Interventions
- Vascular Access
- Medical Device Technology
Background:
- Catheter-based interventions are less invasive but create large arteriotomies.
- Current closure methods for large arteriotomies (10-22 Fr) are often suture-based.
- Access-site complications are common with existing closure devices.
Purpose of the Study:
- To introduce the MANTA vascular closure device (VCD).
- To describe the design concept and practical use of the MANTA VCD.
- To present preliminary clinical experience with the MANTA VCD for large arteriotomy closure.
Main Methods:
- Technical report detailing the MANTA VCD.
- Discussion of the device's design and collagen-based closure mechanism.
- Review of preliminary clinical data and procedural steps.
Main Results:
- The MANTA VCD is designed for arteriotomies ranging from 10 to 22 Fr.
- Preliminary clinical experience suggests feasibility and potential benefits.
- The device targets a specific need in large bore arteriotomy closure.
Conclusions:
- The MANTA VCD represents a novel approach to percutaneous closure of large arteriotomies.
- This collagen-based device may offer an alternative to suture-based techniques.
- Further clinical evaluation is warranted to confirm its efficacy and safety profile.

