Relationship between plasma level of vitamin D and post operative atrial fibrillation in patients undergoing CABG

Area of Science:

• Cardiology
• Endocrinology
• Surgical Medicine

Background:

• Atrial fibrillation (AF) is a common complication following cardiac surgery, particularly coronary artery bypass grafting (CABG).
• Vitamin D's role in cardiovascular health is increasingly recognized, yet its specific association with postoperative AF remains unclear.
• Existing research presents conflicting findings regarding vitamin D levels and AF incidence.

Purpose of the Study:

• To investigate the relationship between plasma vitamin D levels and the occurrence of atrial fibrillation (AF) in patients undergoing coronary artery bypass surgery (CABG).
• To determine if preoperative or postoperative vitamin D status is a significant predictor of AF development after CABG.

Main Methods:

• A cross-sectional study involving 50 patients who underwent CABG surgery.
• Patients were divided into two groups: 25 who developed AF within 48 hours post-CABG (case group) and 25 who did not (control group).
• Plasma vitamin D levels were measured and compared between the case and control groups; data were analyzed using SPSS software.

Main Results:

• No significant differences were observed in demographic characteristics, comorbidities, lipid profiles, or kidney function between the AF and non-AF groups.
• The mean plasma vitamin D level in the case group was 27.4 ± 2.22 ng/ml, compared to 28.2 ± 1.18 ng/ml in the control group.
• The difference in vitamin D levels between the groups was not statistically significant (p=0.803).

Conclusions:

• Plasma vitamin D levels were comparable in patients with and without postoperative atrial fibrillation following CABG.
• This study found no statistically significant association between vitamin D levels and the incidence of atrial fibrillation after coronary artery bypass surgery.
• Further research may be needed to explore other potential factors influencing postoperative AF.