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Association Between Complete Blood Count Parameters and Urinary Stone Disease
Ozay Demiray1, Erdem Cevik2, Ferhat Cuce3
1Department of Urology, Van Military Hospital, Van Askeri Hastanesi, Altintepe, Van, Turkey.
Insights
Complete blood count (CBC) parameters can help diagnose urinary stone disease. Specific CBC markers like increased white blood cell count and red cell distribution width may indicate the presence of urinary stones.
Area of Science:
- Urology
- Nephrology
- Hematology
Background:
- Urinary stone disease is a prevalent health issue.
- Complete blood count (CBC) parameters are routinely analyzed and may offer insights into various medical conditions.
- The potential predictive value of CBC parameters in diagnosing urinary stone disease warrants investigation.
Purpose of the Study:
- To investigate the association between complete blood count (CBC) parameters and the presence of urinary stone disease.
- To determine if CBC findings can aid in the diagnosis of urinary stones.
Main Methods:
- A retrospective observational study included 353 patients with confirmed urinary stone disease or controls.
- Patients underwent ultrasonography (USG) and/or non-contrast computerized tomography (NCCT) and CBC analysis.
- Exclusion criteria included non-urinary inflammatory diseases, fever, infection, anemia, or hematologic malignancy.
Main Results:
- Elevated Red Cell Distribution Width (RDW), Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), White Blood Cell (WBC) count, and granulocyte percentage were significantly associated with urinary stone disease.
- A decreased lymphocyte percentage was also linked to urinary stone disease.
- Microscopic hematuria showed a strong association with urinary stones, with an odds ratio of 67.7 for prediction.
Conclusions:
- Complete blood count (CBC) parameters can serve as supportive indicators for diagnosing urinary stone disease.
- Considering CBC results alongside clinical evaluation, particularly flank pain, may enhance diagnostic accuracy for urinary stones.
Background:
Complete blood count (CBC) parameters may associated with multiple diseases. Urinary stone disease is common public problem. Predictive value of CBC parameters may be associated with urinary stone disease.
Objectives:
To analyze the association between complete blood count (CBC) parameters and urinary stone disease.
Patients And Methods:
This study was a retrospective observational study of 3,099 patients who were admitted to the urology outpatient clinic or diagnosed with urinary stone disease in the emergency services department. There were 353 patients included in the study that had ultrasonography (USG) and/or non-contrast computerized tomography (NCCT) and a CBC. Patients who had non-urinary system inflammatory disease in USG or NCCT, had fever, non-urinary system infection, anemia or diagnosed hematologic malignancy were excluded (n = 27). Patients were divided into two groups: a stone group (n = 74) and a control group (n = 252). Data of patients were retrieved from the hospital database and statistical analysis was performed.
Results:
An increase in RDW, MPV, PDW, WBC, granulocyte percentage and a decrease in lymphocyte percentage is statistically associated with urinary stone disease (P < 0,001, P < 0.001, P = 0.006, P < 0.001, P = 0.003, P = 0.034, respectively). Microscopic hematuria is associated with urinary stone disease and the odds ratio for urinary stone prediction is 67.7 (P < 0.001). In addition, none of the CBC parameters were associated with stone burden.
Conclusions:
When evaluating flank pain in patients, it is important to remember that CBC parameters may support urinary stone disease, and considering CBC results may be useful in the diagnosis of urinary stone disease.
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