Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein-protein Interfaces02:04

Protein-protein Interfaces

14.9K
Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
14.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An analytical revision of the bio-functional layer/electrolyte interface and modelling of dynamic signal transduction in two-dimensional BioFETs.

Nanoscale·2026
Same author

Design of a flexible aromatic gate to immobilize C<sub>60</sub> in a ferritin cage.

Chemical communications (Cambridge, England)·2026
Same author

Detection of skatole using a phage display-derived peptide-modified graphene FET.

Talanta·2026
Same author

Surgical Complications in Hirschsprung Disease and the Impact of Botulinum Toxin Injection on Hirschsprung-Associated Enterocolitis.

Journal of clinical medicine·2026
Same author

Effect of Salts on the Aggregation and Strength of Protein-Based Underwater Adhesives.

ACS omega·2025
Same author

Stratifying Treatment-Resistant Monosymptomatic Nocturnal Enuresis: Identifying the Subgroup Most Responsive to Biofeedback Therapy.

Diagnostics (Basel, Switzerland)·2025

Related Experiment Video

Updated: Mar 14, 2026

Bridging the Bio-Electronic Interface with Biofabrication
16:38

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

17.4K

Bioelectronic interfaces by spontaneously organized peptides on 2D atomic single layer materials.

Yuhei Hayamizu1,2,3, Christopher R So1, Sefa Dag1

  • 1GEMSEC, Genetically Engineered Materials Science and Engineering Center, Materials Science and Engineering, University of Washington, Seattle, WA 98195, USA.

Scientific Reports
|September 23, 2016
PubMed
Summary

Biological molecules self-assemble into nanowires on nanosheets, creating electronic networks. This biomolecular doping integrates biology with nano-electronics for self-assembled bionanoelectronic devices.

More Related Videos

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules
10:27

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules

Published on: August 25, 2009

11.9K
A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
10:42

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Published on: February 27, 2019

9.9K

Related Experiment Videos

Last Updated: Mar 14, 2026

Bridging the Bio-Electronic Interface with Biofabrication
16:38

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

17.4K
Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules
10:27

Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules

Published on: August 25, 2009

11.9K
A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
10:42

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Published on: February 27, 2019

9.9K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biotechnology

Background:

  • The integration of biological molecules with solid materials is key for bottom-up bionanoelectronic devices.
  • Biomolecular self-assembly enables the creation of intricate nanoarchitectures on surfaces.

Purpose of the Study:

  • To demonstrate the self-assembly of peptides into nanowires on 2D nanosheets (graphene and MoS2).
  • To investigate the electronic properties and potential applications of these self-assembled peptide nanostructures.

Main Methods:

  • Combinatorial selection of dodecapeptides and their variants.
  • Characterization of peptide self-assembly on single-layer graphene and molybdenum disulfide (MoS2).
  • Analysis of electronic junctions and doping effects induced by peptide nanowires.

Main Results:

  • Peptide variants self-assemble into nanowires on graphene and MoS2.
  • These nanowires form electronic junctions and create self-assembled electronic networks on graphene.
  • Peptide nanowires on MoS2 alter its electrical conductivity and photoluminescence.

Conclusions:

  • Self-assembled peptide nanostructures can spatially dope 2D nanosheets.
  • This biomolecular doping is a foundational step towards fully self-assembled bionanoelectronic devices.
  • Peptide-nanosheet integration offers a novel pathway for advanced electronic applications.