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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
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Related Experiment Video

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Whole Body Vibration Methods with Survivors of Polio
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Vibration training improves disability status in multiple sclerosis: A pretest-posttest pilot study.

Feng Yang1, Edson F Estrada1, Maria C Sanchez1

  • 1Department of Kinesiology, University of Texas at El Paso, El Paso, TX 79968, USA.

Journal of the Neurological Sciences
|September 23, 2016
PubMed
Summary
This summary is machine-generated.

Vibration training significantly reduced disability in multiple sclerosis (MS) patients. An 8-week program improved functional and cognitive scores, suggesting it

Keywords:
MobilityMultiple Sclerosis Functional CompositePatient Determined Disability StatusSide-alternating vibration

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Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Biomedical Engineering

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease causing progressive disability.
  • Current treatments aim to manage symptoms and slow disease progression, but effective rehabilitation strategies are continually sought.

Purpose of the Study:

  • To investigate the impact of an 8-week vibration training program on disability levels in individuals with multiple sclerosis (MS).

Main Methods:

  • Twenty-five adults with confirmed MS participated in an 8-week training program using a side-alternating vibration platform (20Hz, 2.6mm displacement).
  • Disability was assessed pre- and post-training using the Patient Determined Disability Steps (PDDS) and the MS Functional Composite (MSFC) scores.

Main Results:

  • The vibration training program led to significant improvements in both PDDS scores (p=0.009) and MSFC scores (p<0.0001).
  • All components of the MSFC, including lower extremity function (p=0.011), upper extremity function (p=0.053 for dominant, p=0.059 for non-dominant hand), and cognitive function (p=0.004), showed improvement.

Conclusions:

  • Vibration training appears to be a promising therapeutic modality for reducing disability in people with MS.
  • This non-invasive approach offers a potential complementary strategy to existing MS management protocols.