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Cardiac Changes in Overweight and Obese Patients

Teodora Gabriela Alexescu, Angela Cozma, Adela Sitar-Tăut

    Romanian Journal of Internal Medicine = Revue Roumaine De Medecine Interne
    |September 23, 2016
    PubMed

    Insights

    Overweight and obese individuals show increased risks of early cardiac changes, including diastolic dysfunction and thickened heart structures. These findings highlight the need for proactive cardiovascular monitoring in these populations.

    Area of Science:

    • Cardiology
    • Obesity Medicine

    Background:

    • Rising prevalence of obesity and overweight conditions globally.
    • Significant association of these conditions with cardiovascular complications and mortality.

    Purpose of the Study:

    • To identify and diagnose early cardiac alterations in overweight and obese patients.
    • To investigate the relationship between body mass index and cardiac structural/functional changes.

    Main Methods:

    • Cross-sectional, analytical, and observational study.
    • Inclusion of 111 subjects: 27 normal weight, 84 overweight/obese.
    • Utilized clinical examination, biochemical tests, and 2D echocardiography.

    Main Results:

    • Diastolic dysfunction is 2-5 times more frequent in overweight/obese individuals compared to normal weight.
    • Interventricular septum thickness correlates with body mass index (BMI).
    • Elevated left ventricle mass and mass-to-surface ratio are linked to diastolic dysfunction and BMI.

    Conclusions:

    • Overweight and obese patients exhibit early cardiac changes not seen in normal weight individuals.
    • Key cardiac alterations include decreased ejection fraction, diastolic dysfunction, septal thickening, and increased left ventricle mass.
    • These findings underscore the importance of early cardiac assessment in managing obesity-related cardiovascular risks.
    Abstract

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