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Published on: June 13, 2025
[Management of pediatric patients with esophageal varices]
Sofía Verdaguer D1, Juan Cristóbal Gana A2
1Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Insights
Pediatric gastroenterologists commonly screen for esophageal varices and use beta blockers for prophylaxis in portal hypertension. However, approaches to managing variceal bleeding and secondary prophylaxis vary among specialists.
Area of Science:
- Pediatric Gastroenterology
- Hepatology
- Clinical Management
Background:
- Limited high-quality research exists on diagnosing esophageal varices and managing variceal bleeding in pediatric portal hypertension.
- There is a lack of consensus and evidence-based guidelines for managing these pediatric patients.
Purpose of the Study:
- To investigate the practices and preferences of pediatric gastroenterologists in Chile regarding the management of portal hypertension in children.
- To understand current approaches to screening, prophylaxis, and treatment of variceal bleeding in this population.
Main Methods:
- An online survey was distributed to pediatric gastroenterologists in Chile.
- The survey assessed physician approaches to screening for esophageal varices, primary prophylaxis, and initial management of variceal bleeding.
Main Results:
- 83% of surveyed physicians screen for esophageal varices in children with clinical signs of portal hypertension.
- Beta-blockers are the primary choice for prophylaxis (80%), while octreotide, proton pump inhibitors, and endoscopy are common for initial bleed management.
- Band ligation and beta blockers are favored for secondary prophylaxis, with TIPS and transplantation considered for recurrent bleeding.
Conclusions:
- Most Chilean pediatric gastroenterologists advocate for endoscopic screening and prophylaxis for esophageal varices in portal hypertension.
- Significant variations exist in the choice of secondary prophylaxis and the initial management strategies for variceal bleeding.
Background:
There is a paucity of good quality research about the diagnosis of esophageal varices and the prophylaxis and treatment of variceal bleeding in pediatric patients with portal hypertension There is little consensus and practically no evidence-based approach about the management of these patients.
Aim:
To describe the behavior and preferences of pediatric gastroenterologists in Chile in the management of portal hypertension in children.
Material And Methods:
An online survey was sent to Chilean pediatric gastroenterologists, with questions evaluating the physicians approaches to screening of esophageal varices in children with portal hypertension, and their preferred methods of prophylaxis and initial management of variceal bleeding.
Results:
Thirty five of 69 contacted physicians answered the survey (51%). Twenty nine pediatric gastroenterologists (83%) screen for esophageal varices in patients with clinical evidence of portal hypertension, and 12 (34%) in every patient with chronic liver disease. Twenty eight respondents (80%) use primary prophylaxis, mainly beta blockers. Octreotide, proton pump inhibitors and endoscopy are the most common practices in the initial management of an esophageal varix bleed. The methods mostly used as secondary prophylaxis are band ligation and beta blockers. In the case of recurrent hemorrhage, besides band ligation, management with Transjugular Intrahepatic Portosystemic Shunt (TIPS) and hepatic transplantation are more likely.
Conclusions:
Even though most pediatric gastroenterologists in this survey are inclined to offer endoscopic screening of esophageal varices and prophylaxis to patients with portal hypertension, this is not a universal behavior. There are different approaches mainly in the election of secondary prophylaxis and the initial management of variceal bleeding.
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