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Updated: Mar 14, 2026

Production and Targeting of Monovalent Quantum Dots
Published on: October 23, 2014
One-pot synthesis of nitrogen and sulfur co-doped carbon dots and its application for sensor and multicolor cellular
Jiucun Chen1, Jianhua Liu2, Junzhi Li2
1Institute for Clean Energy & Advanced Materials, Faculty of Materials and Energy, Southwest University, Chongqing 400715, China; Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.
Abstract:
Nitrogen and sulfur co-doped carbon dots (N, S/C-dots) were prepared via one-pot hydrothermal treatment of citric acid and cystamine dihydrochloride. The as-prepared N, S/C-dots exhibited excellent excitation-wavelength-independent photoluminescence property and higher fluorescence quantum yield (QY) of 39.7% compared to C,N-dots (QY=2.6%) prepared using citric acid and 1,6-diaminohexane dihydrochloride as the precursor. The N, S/C-dots were well-dispersed in aqueous solution and showed good photoluminescence stabilities in different pH and temperature without any surface modification. Additionally, the fluorescence of N, S/C-dots can be quenched based on inner filter effect (IFE) upon the addition of Cr(VI) and showed good selectivity and sensitivity to Cr(VI). The detection for Cr(VI) exhibited a good linear correlation ranging from 1 to 80μM with a detection limit of 0.86μM. What's more, in comparison with other quantum dots and organic dyes, these N, S/C-dots were much more eco-friendly and can be used for multicolor bioimaging.

